Research

These research study papers and articles have been sourced from a reputable British, European, American and Chinese electronic medical database.

Fertility

Effects of acupuncture and moxa treatment in patients with seamen abnormalities
Gurfinkel E, Cedenho AP, Yamamura Y, Srougi M. (Asian J Androl 2003 Dec;5(4):345 -8)
*Prospective, controlled, blind study.* 19 man with idiopathic oligospermia (too few sperm), asthenospermia (poor motility) or teratozoospermia (poor morphology), randomised into two groups. Both groups given acupuncture and moxibustion, the treatment group at ’ therapeutic’ points and the control group at ‘indifferent’points.

* Treatment lasted ten weeks (25 min of acupuncture and 20 min of moxibustion, twice a week)

Conclusion: After treatment significant increase in % of normal-form sperm in treatment group compared to control.

 

Influence of acupuncture on idiopathic male infertility in assisted reproductive technology
J Huanzhong Univ Sci Technology Med Sci 2002;22(3):228-30. Zhang M, Huang G, Lu F, Paulus WE, Sterzik K.
* 22 patients who failed in intracytoplasmic sperm injection (ICSI) with idiopathic male infertility were treated with acupuncture twice weekly for 8 weeks followed by ICSI treatment again.* The sperm concentration motility, morphology, fertilization rates and embryo quality were observed. Sperm motility after acupuncture was significantly improved as compered with that before treatment. The normal sperm ratio was increased after acupuncture. The fertilization rate after acupuncture (66.2%) were obviously higher then that before treatment (40.2%, P<0.01).There was no significant difference in sperm concentration before and after acupuncture. The embryo quality after acupuncture was improved, but the difference between them was not significant (P>0.05)

Conclusion: Acupuncture can improve sperm quality and fertilization rates in assisted reproductive technology.

 

Quantitative evaluation of spermatozoa ultrastructure after acupuncture treatment for idiopathic male infertility
Jian Pei, Strehler, Ulrich Noss, Markus Abt, Paola Piomboni, Baccio Baccetti and Karl Sterzik,( Fertility and Sterility, vol 84, issue 1, July 2005, pp141-147)
* 40 German men with idiopathic oligospermia (too few sperm), asthenospermia (poor motility) or teratozoospermia (poor morphology).* 28received acupuncture twice a week for 5 weeks. Compared to 12in the untreated control group.* After treatment there was a significant improvement in the percentage and number of normal morphology sperm (particularly head and mid- piece of tail). Improvement in total motility was (from 44.5% to 50%)Conclusion: The treatment of idiopathic male infertility could benefit from employing acupuncture. A general improvement of sperm quality, specifically in the ultrastructural integrity of spermatozoa, was seen after acupuncture, although we did not identify specific sperm pathologies that could be particularly sensitive to this therapy.

 

Influence of acupuncture on the pregnancy rate in patients who undergo assisted reproduction therapy
Wolfgang E. Paulus, M.D., Mingmin Zhang M.D. Erwin Strehler M.D., Imam El-Dansouri, Ph.D., Karl Sterzik M.D.Fertility and Sterility Vol. 77, NO.4, April 2002.
* Prospective randomized study* 160 patients who were undergoing ART and who had good quality embryos were divided into two groups by comparing a group of patients receiving acupuncture treatment shortly before and after embryo transfer (ET) with a control group receiving no acupuncture.* There were no between-group differences regarding patient characteristics, numbers of previous IVF and intra-cytoplasmic sperm injection (ICSI) treatments, endometrial thickness on the day of transfer or the pulsatility index (PI) before and after ( ET).The clinical pregnancy rate, however, was significantly in favour of acupuncture: 26.3% (control) versus 42.5% (P=0.03).

Conclusion: The authors concluded that acupuncture at the time of ET improves the clinical pregnancy rate in IVF/ICIS patients.

 

Effect of acupuncture on the outcome of in vitro fertilization and intracytoplasmic sperm injection: a randomized, prospective, controlled clinical study.
Dieterle S, Ying G, Hatzmann W, Neuer A. Fertil Steril 2006; 85(5): 1347-51.
* Dieterle et al randomised 116 patients to receive acupuncture (n=116) or placebo acupuncture (n=109). Both groups received two acupuncture treatments, one after ET and a second one three days later. The points in the placebo acupuncture group were designed not to influence fertility.* The pregnancy outcome differed significantly between the acupuncture group (28.4%) and the placebo group (13.8%) (P=0.01).Conclusion: The authors concluded that acupuncture significantly improves the IVF/ICSI outcome and that acupuncture might be complementary option for patients undergoing IVF/ICSI even though further evidence is needed.

 

Anovulatory Infertility
Gao Xiu-ling , Shan Xi Zhong Yi (Shanxi Chinese Medicine Publishing), 2005; 34(5)
* A total of 60 infertility patients were randomly divided into two groups, a treatment group and a comparison group. In the treatment group, there were 18 cases who had never conceived and 12 cases who had previously conceived but had not conceived for the past two years. Three cases were20-25 years old, 13 cases were 26-30 years old, nine cases were 31-35 years old and five cases were 36-40. The course of disease was from 2.5-18 years, with average disease duration of 7.6 years.* In the comparison group, 20 cases had never conceived and 10cases had previously conceived but not for the last two years. Two cases were 20-25 years old, 15 cases were 26-30 years old, 10 casesWere 31-35 years old three cases were 36-40 years old. The course of the disease was 2.6-17 years,

With an average duration of 7.8 years. The two groups showed no marked statistical differences in their data and, thus, were considered comparable for the propose of this study.

* On the fifth day of the menstrual cycle, the comparison group began taking 50 milligrams of Clomid orally each day for five days. If they did not become pregnant, the treatment was repeated for a total of three months and then stopped. They were then observed for three additional months

In addition to the basic treatment of the comparison group, the treatment group also took’ Benefit the Feminine’ Chinese herbal medicine decoction.

Conclusion: In the study Clomid’s rate of re-establishing ovulation was 73.3% and 23.3% of these patients become pregnant within six months.

Using integrated Chinese-western medicine, the rate of re-establishing ovulation was 93.3% and 43.3% of these patients become pregnant within six month. Using the integrated Chinese- Western medical treatment showed promising results

 

Effects of acupuncture and stabilising exercises as adjunct to standard treatment in pregnant women with pelvic girdle pain: randomised single blind controlled trial
Helen Elden, Lars Ladfors, Monika Fagevik Olsen, Hans-Christian Ostgaard, Henrik Hagberg , BMJ, 2005, Volume 330: 761